Scientists reverse ageing in mammals and predict human trials within 10 years
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An end to grey hair and crows-feet could be just 10 years away after scientists showed it is possible to reverse ageing in animals. Using a new technique which takes adult cells back to their embryonic form, US researchers at the Salk Institute in California, showed it was possible to reverse ageing in mice, allowing the animals to not only look younger, but live for 30% longer.
The technique involves stimulating four genes which are particularly active during development in the womb. In addition, it helps to turn the clock back on human skin cells in the lab, making them look and behave younger.
Scientists hope to eventually create a drug which can mimic the effect of the found genes which could be taken to slow down, and even reverse the ageing process. They say it will take around 10 years to get to human trials.
Dr Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory said "Our study shows that ageing may not have to proceed in one single direction, with careful modulation, aging might be reversed."
Scientists have already known that the four genes, which are known collectively as the Yamanaka factors, could turn adult cells back to their stem cell state, where they can grow into any part of the body.

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But it was always feared that allowing that to happen could damage organs made from the cells, and even trigger cancer. However, One of the worrying is that stimulating the genes intermittently reversed ageing, without causing any damaging side effects.
The breakthrough could also help people stay healthier for longer. The ageing population means that the risk of developing age-related diseases, such as dementia, cancer and heart disease also rises. But if the body could be kept younger for longer then it could prevent many deadly diseases for decades.

Last edited by Lchaning (2016-12-25 00:38:43)